Publications
] Characterization of IS1676 from Rhodococcus erythropolis SQ1. Appl Microbiol Biotechnol 52, 811-9 (1999).
Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl Environ Microbiol 65, 3100-7 (1999).
Flux through the tetrahydrodipicolinate succinylase pathway is dispensable for L-lysine production in Corynebacterium glutamicum. Appl Microbiol Biotechnol 51, 325-33 (1999).
Isolation and characterization of indene bioconversion genes from Rhodococcus strain I24. Appl Microbiol Biotechnol 51, 786-93 (1999).
Metabolite and isotopomer balancing in the analysis of metabolic cycles: II. Applications. Biotechnol Bioeng 62, 392-401 (1999).
Metabolite and isotopomer balancing in the analysis of metabolic cycles: I. Theory. Biotechnol Bioeng 62, 375-391 (1999).
PHA synthase from chromatium vinosum: cysteine 149 is involved in covalent catalysis. Biochemistry 38, 826-37 (1999).
Redirection of carbon flux to lysine in a recombinant of Corynebacterium lactofermentum ATCC 21799 by limited supply of pantothenate. J Biosci Bioeng 88, 168-72 (1999).
Growth factor and bcl-2 mediated survival during abortive proliferation of hybridoma cell line. Biotechnol Bioeng 57, 164-71 (1998).
Sequence of the Corynebacterium glutamicum pyruvate carboxylase gene. Appl Microbiol Biotechnol 50, 346-52 (1998).
Extension of Sp2/0 hybridoma cell viability through interleukin-6 supplementation. Biotechnol Bioeng 55, 439-46 (1997).
Metabolic and physiological studies of Corynebacterium glutamicum mutants. Biotechnol Bioeng 55, 864-79 (1997).
PHA synthase activity controls the molecular weight and polydispersity of polyhydroxybutyrate in vivo. Nat Biotechnol 15, 63-7 (1997).
Effect of different levels of aspartokinase on the lysine production by Corynebacterium lactofermentum. Appl Microbiol Biotechnol 43, 76-82 (1995).
Effect of inducible thrB expression on amino acid production in Corynebacterium lactofermentum ATCC 21799. Appl Environ Microbiol 61, 74-8 (1995).
Intracellular flux analysis applied to the effect of dissolved oxygen on hybridomas. Appl Microbiol Biotechnol 44, 27-36 (1995).
Measurement of glutathione redox state in cytosol and secretory pathway of cultured cells. Methods Enzymol 251, 212-21 (1995).
Production of isoleucine by overexpression of ilvA in a Corynebacterium lactofermentum threonine producer. Appl Microbiol Biotechnol 43, 482-8 (1995).
Purification and properties of oxaloacetate decarboxylase from Corynebacterium glutamicum. Antonie Van Leeuwenhoek 67, 221-7 (1995).
Recent advances in the physiology and genetics of amino acid-producing bacteria. Crit Rev Biotechnol 15, 73-103 (1995).
Regulated secretion of prolactin by the mouse insulinoma cell line beta TC-3. Biotechnology (N Y) 13, 1191-7 (1995).
Cloning of the pyruvate kinase gene (pyk) of Corynebacterium glutamicum and site-specific inactivation of pyk in a lysine-producing Corynebacterium lactofermentum strain. Appl Environ Microbiol 60, 2494-500 (1994).
The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin. Cytotechnology 15, 195-208 (1994).
Overexpression and purification of the soluble polyhydroxyalkanoate synthase from Alcaligenes eutrophus: evidence for a required posttranslational modification for catalytic activity. Biochemistry 33, 9311-20 (1994).
Structural and functional analysis of pyruvate kinase from Corynebacterium glutamicum. Appl Environ Microbiol 60, 2501-7 (1994).
The DNA sequence and minimal replicon of the Corynebacterium glutamicum plasmid pSR1: evidence of a common ancestry with plasmids from C. diphtheriae. J Gen Microbiol 139, 1753-9 (1993).
Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon. J Bacteriol 175, 4096-103 (1993).
The AP-1 site at -150 bp, but not the NF-kappa B site, is likely to represent the major target of protein kinase C in the interleukin 2 promoter. J Exp Med 175, 853-62 (1992).
Biosynthetic thiolase from Zoogloea ramigera. Mutagenesis of the putative active-site base Cys-378 to Ser-378 changes the partitioning of the acetyl S-enzyme intermediate. J Biol Chem 267, 16041-3 (1992).
Cloning and sequencing the Lactobacillus brevis gene encoding xylose isomerase. Gene 114, 127-32 (1992).
Expression, secretion, and processing of staphylococcal nuclease by Corynebacterium glutamicum. J Bacteriol 174, 1854-61 (1992).
Biosynthetic thiolase from Zoogloea ramigera. Evidence for a mechanism involving Cys-378 as the active site base. J Biol Chem 266, 8369-75 (1991).
The molecular structure of the Corynebacterium glutamicum threonine synthase gene. Mol Microbiol 4, 1693-702 (1990).
Nucleotide sequence and organization of the upstream region of the Corynebacterium glutamicum lysA gene. Mol Microbiol 4, 1819-30 (1990).
Use of regulated secretion in protein production from animal cells: an evaluation with the AtT-20 model cell line. Biotechnol Bioeng 35, 771-80 (1990).
Fine structural analysis of the Zoogloea ramigera phbA-phbB locus encoding beta-ketothiolase and acetoacetyl-CoA reductase: nucleotide sequence of phbB. Mol Microbiol 3, 349-57 (1989).
Mathematical descriptions of hybridoma culture kinetics: II. The relationship between thiol chemistry and the degradation of serum activity. Biotechnol Bioeng 33, 440-50 (1989).
Mechanistic studies on beta-ketoacyl thiolase from Zoogloea ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic characterization of wild-type and mutant enzymes. Biochemistry 28, 5735-42 (1989).
Molecular cloning, nucleotide sequence and fine-structural analysis of the Corynebacterium glutamicum fda gene: structural comparison of C. glutamicum fructose-1,6-biphosphate aldolase to class I and class II aldolases. Mol Microbiol 3, 1625-37 (1989).
The phosphoenolpyruvate carboxylase gene of Corynebacterium glutamicum: molecular cloning, nucleotide sequence, and expression. Mol Gen Genet 218, 330-9 (1989).